Krios G4 Cryo-TEM

Atomic resolution cryo-EM with enhanced productivity and compact design

he award-winning Thermo Scientific Krios G4 Cryo-Transmission Electron Microscope (Cryo-TEM) enables you to unravel life at the atomic level—easier, faster, and more reliably than ever before. The most compact TEM in its class, the Krios G4 Cryo-TEM consists of a highlTy stable 300 kV TEM platform and the industry-leading Autoloader (a cryogenic sample manipulation robot), making it ideally suited for automated applications such as cryo-electron tomography (cryo-ET), single-particle analysis (SPA), and micro-electron diffraction (MicroED).

 

 

 

Features

Truly atomic resolution performance

The optional Selectris X Imaging Filter with Falcon 4i Direct Electron Detector and E-CFEG cold field emission source improve image contrast to reach higher resolutions in shorter time.

Maximized productivity through automation

Advanced Performance Monitoring ensures the best optical starting point for automated runs and Thermo Scientific Smart EPU Software enables automated grid screening, quality monitoring, and data management.

Workflow connectivity

Designed for easy exchange of cassettes, facilitating a smooth transfer of specimens between Autoloader-equipped TEM instruments, and equipped with Thermo Scientific Athena Software to manage experimental parameters and data.

Easier to fit into new or existing labs

Redesigned internal base frame and system enclosure reduce height below 3 m (10 ft) while enhancing system performance and preventing costly room renovations.

 

Specifications

Source

• X-FEG (extreme high-brightness field emission gun) or low-energy-spread cold FEG
(E-CFEG)

 

Accelerating Voltage

• 80–300 kV

Cryo-autoloader

• Automated and contamination-free loading of cassettes (up to 12 grids)

Stage

• Computerized 4-axis specimen stage with ±70-degree alpha tilt
• Cryo-stage with single axis holder for optimized stability and drift performance

Imaging

• Rotation-free imaging with changing magnification

Detectors (optional)

• Falcon 4 Direct Electron Detector
• Thermo Scientific Ceta™ D Camera
• Thermo Scientific Ceta 16M Camera
• HAADF STEM detectors
• On-axis BF/DF detectors

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