Talos L120C G2 (S)TEM
Versatile TEM and STEM microscope for 2D and 3D visualization of beam sensitive samples and materials using high contrast.
The Thermo Scientific Talos L120C G2 (S)TEM is a 20-120 kV thermionic (scanning) transmission electron microscope specifically designed to deliver high performance and productivity across a broad range of samples and applications. It excels in both 2D and 3D imaging of biological structures, such as cells and organelles, as well as materials like asbestos, polymers, and soft substances, under ambient or cryogenic conditions. The Talos L120C simplifies the process of obtaining high-quality results, regardless of the user’s experience level. Its intuitive user interface streamlines routine 2D imaging, while advanced automation supports sophisticated 3D imaging workflows with excellent TEM and STEM resolution, enabling researchers to focus on their scientific inquiries instead of instrument operation.
The Talos L120C elevates imaging capabilities with its optional cryo-box and low-dose techniques, allowing for high-quality imaging of cryo-preserved samples and beam-sensitive materials. The cryo-box ensures maximum protection of cryo-specimens, reducing ice contamination even during extended data collection sessions of over 8 hours.
To enhance productivity in multi-user and multi-application settings, the motorized, retractable cryo-box allows effortless switching between cryo-EM, STEM, and EDS analysis. The large C-Twin lens pole-piece gap provides high contrast and supports specimen tilts up to 90°, while the constant-power objective lens ensures rapid, reproducible mode changes and high-tension adjustments in seconds.
Overall, the Talos L120C (S)TEM offers exceptional versatility, combining a consistently reliable electron column with advanced capabilities for high-resolution 3D characterization, in situ dynamic observation, EDS analysis, and high-contrast imaging, particularly in cryo-TEM applications.
Talos L120C (S)TEM automation
Designed for multi-user and multi-discipline environments and equipped with a familiar UI shared across all Thermo Scientific TEM platforms, the Talos L120C TEM is ideal for novice and expert users alike. All daily TEM tunings have been automated to provide the best and most reproducible setup, easing the learning curve for novice operators and improving time-to-data for experienced users. The Talos L120C TEM also offers educational online help embedded within the UI. Additionally, Thermo Scientific application software packages facilitate intuitive settings and automated data collection for different use cases and workflows, such as large area 2D imaging, energy dispersive X-ray analysis, single particle analysis, MicroED and tomography.
Explore cellular ultrastucture Characterize nanoparticles 2D thin section of muscle tissue
Features
Versatile multi-application system
Designed for routine TEM and STEM imaging and characterization of a variety of samples, including resin embedded cells, soft materials, nanoparticles, and protein complexes at ambient and cryo-conditions.
High quality images
High-contrast, high-quality TEM and STEM imaging by simultaneous, multiple signal detection with up to four-channel-integration STEM detectors.
Cryo-imaging
Retractable, motorized cryo-box and low-dose technique enable superior imaging of samples at cryogenic temperatures while preserving the possibility of STEM imaging and EDS analysis applications.
Chemical composition data
Flexible energy-dispersive X-ray spectroscopy (EDS) analysis for chemical information.
Space for more
Add tomography or in situ sample holders compatible with a large analytical pole piece gap allowing up to ±90° stage tilt range and ±375 µm stage height range.
Improved productivity and reproducibility
Ultra-stable column, SmartCam remote operation, and constant power objective lenses for quick mode and high-tension switches. Fast, easy switching for multi-user environments.
Auto-alignments
All daily TEM tunings—such as focus, Eucentric height, center beam shift, center condenser aperture, and rotation center—are automated.
Automated data collection
Automate single particle analysis imaging with Thermo Scientific EPU Software and tomography with Thermo Scientific Tomo 5 Software. Collect large area 2D images at different image resolutions using Thermo Scientific Maps Software with automatic image acquisition and stitching while documenting the overall context and entire area of the region of interest with exceptional quality.
Ceta CMOS Camera
The 4K × 4K Thermo Scientific Ceta CMOS Camera with large field of view enables live digital zooming with high sensitivity and high speed over the entire high-tension range. Specialized Ceta Cameras are available for low-dose imaging (Ceta-S and Ceta-F) and for MicroED (Ceta-D) applications.
Compact design
Smaller footprint and dimensions mean this tool can be accommodated into more challenging spaces while reducing infrastructure and support costs.
Specifications
• ≤0.204 nm
• ≤0.37 nm
• ≤1.0 nm (with LaB6)
• Standard: 25–650k ×
• Enhanced: 35–910k ×
• 200 – 2.2M×
• ±90°